Thermo Fisher Scientific CD153 Polyclonal Antibody
CD153 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 적합합니다. 비결합(Unconjugated) 형태로 제공되며, 1 mg/mL 농도의 액상 제품입니다. CD30/CD30L 신호전달 연구 및 림프종 관련 연구용으로 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide, corresponding to amino acids 80–130 of Human CD30-L |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803275 |
Target Information
The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin’s disease and other CD30⁺ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin’s and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin’s lymphomas (including Burkitt’s lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4⁺/CD8⁺ thymocytes that coexpress CD45RO and the IL4 receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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