Thermo Fisher Scientific IL-28A/IL-28B Monoclonal Antibody (244716)

Applications and Tested Dilution

ELISA (ELISA)

• Detection: 0.5–2 µg/mL
• Capture: 2–8 µg/mL

Neutralization (Neu)

• 3–9 µg/mL

Product Specifications

Product Specific Information

• In sandwich ELISAs, 100% cross-reactivity with recombinant mouse IL-28A/IFN-lambda 2 is observed.
• No cross-reactivity with recombinant human IL-28A or IL-29.
• Reconstitute at 0.5 mg/mL in sterile PBS.
• Endotoxin level: <0.10 EU per 1 µg of antibody (LAL method).

Target Information

IL28 is a cytokine distantly related to type I interferons and the IL-10 family. The interleukin 28B (IL28B) and interleukin 29 (IL29) genes form a cytokine gene cluster on chromosome 19q13. Expression of these cytokines is induced by viral infection, and all three interact with a heterodimeric class II cytokine receptor composed of IL10RB and IL28RA.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.