Thermo Fisher Scientific IL-28A/IL-28B Monoclonal Antibody (244716)

Applications

Tested Dilution

Publications

ELISA (ELISA)

0.5-2 µg/mL (Detection), 2-8 µg/mL (Capture)

-

Neutralization (Neu)

3-9 µg/mL

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rat / IgG2b

Class

Monoclonal

Type

Antibody

Clone

244716

Immunogen

E. coli-derived recombinant mouse IL-28B/IFN-lambda3 Asp20-Val193 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IL-28A/IL-28B,uniProtId:Q4VK74-1,ncbiNodeId:10090,antigenRange:20-193,antigenLength:193,antigenImageFileName:MA5-23902_IL-28AIL-28B_Q4VK74-1_Rat.svg,antigenImageFileNamePDP:MA5-23902_IL-28AIL-28B_Q4VK74-1_Rat_PDP.jpeg,sortOrder:1},{targetFamily:IL-28A/IL-28B,uniProtId:Q8CGK6-1,ncbiNodeId:10090,antigenRange:20-193,antigenLength:193,antigenImageFileName:MA5-23902_IL-28AIL-28B_Q8CGK6-1_Rat.svg,antigenImageFileNamePDP:MA5-23902_IL-28AIL-28B_Q8CGK6-1_Rat_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2607558

Product Specific Information

In sandwich ELISAs, 100% cross-reactivity with recombinant mouse IL-28A/IFN-lambda 2 and no cross-reactivity with recombinant human (rh) IL-28A or rhIL-29 is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Target Information

IL28 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.