Thermo Fisher Scientific CLN2 Monoclonal Antibody (254008)
CLN2 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 동결건조 형태로 제공되며, PBS 및 5% 트레할로스 용액에 재구성 가능합니다. 인간 시료에 반응하며, 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunoprecipitation (IP)
- Tested Dilution: 25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 254008 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Tripeptidyl-Peptidase I/TPP1 (Ser20–Pro563) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2610430 |
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates and has weaker endopeptidase activity. It is synthesized as a catalytically inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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