Thermo Fisher Scientific ARL15 Polyclonal Antibody
ARL15 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat에 반응합니다. Western blot과 IHC에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. K562 lysate를 양성 대조군으로 권장하며, 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid peptide near the center of human ARL15 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152738 |
Product Specific Information
- A suggested positive control is K562 cell lysate.
- PA5-20779 can be used with blocking peptide PEP-0893.
Target Information
ADP-ribosylation factors (ARFs) are highly conserved guanine nucleotide-binding proteins that enhance the ADP-ribosyltransferase activity of cholera toxin. ARFs are important in eukaryotic vesicular trafficking pathways and play an essential role in the activation of phospholipase D (PC-PLD).
ARL15 (ADP-ribosylation factor-like 15) is a member of the ARF family of the Ras superfamily of small GTPases, involved in multiple regulatory pathways altered in human carcinogenesis. Other related proteins include:
- ARL11: Thought to be a tumor suppressor involved in apoptosis regulation
- ARL2: Plays an important role in microtubule dynamics and cell cycle progression
- ARL4: May play a role in neurogenesis during embryonic development
The gene encoding ARL15 maps to chromosome 5p15 in humans. At least three isoforms of ARL15 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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