Thermo Fisher Scientific G6PD Polyclonal Antibody
Rabbit polyclonal antibody against human G6PD, validated for WB, IHC(P), and ELISA. High specificity and sensitivity with multiple species reactivity. Supplied as liquid, 1.01 mg/mL, purified by antigen affinity chromatography. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| ELISA | 1:1,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 100–322 of Human G6PD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.01 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547137 |
Product Specific Information
- Recommended positive control: Molt-4
- Predicted reactivity: Rat (95%), Xenopus laevis (81%), Rabbit (96%), Rhesus Monkey (100%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes glucose-6-phosphate dehydrogenase (G6PD), a cytosolic enzyme encoded by a housekeeping X-linked gene. Its main function is to produce NADPH, an essential electron donor for defense against oxidative stress and for reductive biosynthetic reactions.
G6PD is genetically diverse, with many variants caused by missense mutations that lead to varying enzyme activity and clinical symptoms. G6PD deficiency may result in neonatal jaundice, acute hemolysis, or chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms are known.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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