Thermo Fisher Scientific ARMC10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ARMC10. Recombinant protein control fragment (Product #RP-90462). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ARMC10,uniProtId:Q8N2F6-1,ncbiNodeId:9606,antigenRange:239-343,antigenLength:343,antigenImageFileName:PA5-52783_ARMC10_Q8N2F6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52783_ARMC10_Q8N2F6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638212

Product Specific Information

Immunogen sequence: LKLLLNLSEN PAMTEGLLRA QVDSSFLSLY DSHVAKEILL RVLTLFQNIK NCLKIEGHLA VQPTFTEGSL FFLLHGEECA QKIRALVDHH DAEVKEKVVT IIPKI

Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 73%.

Target Information

This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.