Thermo Fisher Scientific ARMC10 Polyclonal Antibody
Human ARMC10 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제됨. PBS 기반의 액상 형태로 4°C 또는 -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific ARMC10 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ARMC10. Recombinant protein control fragment (Product #RP-90462). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638212 |
Product Specific Information
Immunogen sequence:
LKLLLNLSEN PAMTEGLLRA QVDSSFLSLY DSHVAKEILL RVLTLFQNIK NCLKIEGHLA VQPTFTEGSL FFLLHGEECA QKIRALVDHH DAEVKEKVVT IIPKI
Highest antigen sequence identity to the following orthologs:
- Mouse: 76%
- Rat: 73%
Target Information
This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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