Thermo Fisher Scientific OLFM4 Polyclonal Antibody
OLFM4 단백질을 인식하는 토끼 폴리클로날 항체로, IHC(P) 실험에 적합합니다. 인간 및 개 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C 단기 보관 가능하며, 장기 보관 시 -20°C에서 냉동 보관을 권장합니다.
- 카탈로그번호
- PA532955
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific OLFM4 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 15–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from internal region of human OLFM4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550416 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Orangutan, Dog (100%)
Gibbon, Monkey, Panda (93%)
Marmoset, Bat (87%)
Hamster, Rabbit, Pig (80%)
Target Information
OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflamed colonic epithelium. It contains one signal peptide and six N-linked glycosylation motifs, forming disulfide-bonded multimers.
OLFM4 may function as a transcription factor with matrix-related roles in differentiation. Constitutive expression in cancer cells allows binding to GRIM-19, a potent apoptosis inducer, conferring antiapoptotic activity and potential as a diagnostic marker for human cancers. Reports indicate OLFM4 promotes proliferation of PANC-1 cells by facilitating transition from S to G2/M phase. Interaction with endogenous cell surface lectins and cadherins may mediate cell adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.