Thermo Fisher Scientific ICOSLG Monoclonal Antibody (OTI2C5), TrueMAB
Human ICOSLG 단백질을 인식하는 마우스 모노클로날 항체로, Western blot과 IHC(P)에서 검증됨. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. ICOSL 단백질 연구 및 T세포 활성화 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C5 |
| Immunogen | Full length human recombinant protein of human ICOSLG produced in HEK293T cell. Target family: CD275 (B7-H2), UniProt ID: O75144-1, Antigen range: 1–302 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
When using this carrier-free antibody for conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Inducible co-stimulator ligand (ICOSL) is a ligand expressed on antigen-presenting cells and peripheral tissue cells that binds to the inducible co-stimulator receptor (ICOS).
ICOS belongs to the CD28/CD152 receptor family, which regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells, and B cells, and can be induced by inflammatory stimuli.
Binding to ICOSL provides a co-stimulatory signal for T-cell proliferation and cytokine secretion.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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