Thermo Fisher Scientific ICOSLG Monoclonal Antibody (OTI2C5), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
When using this carrier-free antibody for conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Inducible co-stimulator ligand (ICOSL) is a ligand expressed on antigen-presenting cells and peripheral tissue cells that binds to the inducible co-stimulator receptor (ICOS).
ICOS belongs to the CD28/CD152 receptor family, which regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells, and B cells, and can be induced by inflammatory stimuli.
Binding to ICOSL provides a co-stimulatory signal for T-cell proliferation and cytokine secretion.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.