Thermo Fisher Scientific NAPSA Monoclonal Antibody (OTI3A4), TrueMAB
인간 NAPSA 단백질(aa 64-244)을 인식하는 Mouse IgG2a 단클론 항체로, IHC(P) 및 ICC/IF에 적합합니다. 무보존제 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다. 폐 및 신장 관련 암 연구에 유용한 특이적 바이오마커 검출용 항체입니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 64–244 of human NAPSA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Napsin 1 is an aspartic protease predominantly expressed in the lung and kidney, and found in metastatic carcinomas. It processes surfactant protein B in healthy tissues but shows altered regulation during carcinogenesis.
Napsin evaluation aids in identifying various cancers and differentiating primary tumors from metastases. Combined with thyroid transcription factor analysis, it serves as a specific biomarker for carcinoma differentiation.
Napsin is also associated with pulmonary alveolar proteinosis and protein catabolism in renal tubules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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