Thermo Fisher Scientific Phospho-GAB2 (Ser159) Polyclonal Antibody
Phospho-GAB2 (Ser159) 특이적 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. Western Blot에 적합하며, Gab1·Gab3에는 교차 반응하지 않습니다. 항원 친화 크로마토그래피로 정제되었고, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer159 of human Gab2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10989207 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with Gab1 or Gab3.
Target Information
This gene belongs to the GRB2-associated binding protein (GAB) family. These proteins contain pleckstrin homology (PH) domains and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The encoded protein is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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