Thermo Fisher Scientific Phospho-STING (Ser366) Polyclonal Antibody
STING 단백질의 Ser366 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체로, WB·IHC·ICC 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. 고순도 정제 및 안정적 액상 형태로 제공되며, 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-STING (Ser366) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 2 publications |
| Immunohistochemistry (IHC) | – | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TMEM173 (Accession Q86WV6), corresponding to amino acid residues around phosphorylated Ser366 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817102 |
Product Specific Information
This antibody detects endogenous levels of TMEM173/STING only when phosphorylated at Ser366.
Target Information
STING is a 379-amino-acid signaling protein that plays a critical role in innate immune signaling. It activates NF-κB and IRF3 transcription pathways, inducing type I interferon (IFN-α and IFN-β) expression and antiviral responses. STING is involved in transduction of apoptotic signals via MHC-II association and may participate in ERK pathway activation. It is localized mainly in the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed in most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-105674_STING_Q86WV6-1_Rabbit.svg, PA5-105674_STING_Q86WV6-1_Rabbit_PDP.jpeg)
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