Thermo Fisher Scientific TRAF3IP1 Polyclonal Antibody
Human TRAF3IP1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 검증 완료. 항원 친화 크로마토그래피로 정제되었으며, 0.2 mg/mL 농도의 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA558142
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TRAF3IP1. Recombinant protein control fragment (Product # RP-96237) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648871 |
Product Specific Information
Immunogen sequence:
ISTRASKSLT TKTSKRRSKN SVEGRKEDNI SAKSLDSIVS GINNEPNQET TTSEIGTKEA NINSTSISDD NSASL
Sequence identity:
- Mouse: 67%
- Rat: 67%
Target Information
Tumor necrosis factor receptor (TNFR) superfamily members transmit signals regulating proliferation, differentiation and apoptosis in various cell types. TNFR-associated factors (TRAFs) are a family of proteins that act as downstream signal transducers of the TNFR superfamily.
TRAF3 contains an N-terminal ring finger/zinc finger region essential for downstream signaling. MIP-T3 (TRAF3IP1) associates with TRAF3, binds to taxol-stabilized microtubules and tubulin in vitro, and recruits TRAF3 to microtubules when both proteins are overexpressed. The MIP-T3/TRAF3 interaction requires the coiled-coil TRAF-N domain of TRAF3, suggesting a potential mechanism for sequestering TRAF3 to the cytoskeletal network.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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