Thermo Fisher Scientific TRAF3IP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TRAF3IP1. Recombinant protein control fragment (Product #RP-96237). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TRAF3IP1,uniProtId:Q8TDR0-1,ncbiNodeId:9606,antigenRange:332-406,antigenLength:691,antigenImageFileName:PA5-58142_TRAF3IP1_Q8TDR0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58142_TRAF3IP1_Q8TDR0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648871

Product Specific Information

Immunogen sequence: ISTRASKSLT TKTSKRRSKN SVEGRKEDNI SAKSLDSIVS GINNEPNQET TTSEIGTKEA NINSTSISDD NSASL

Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 67%.

Target Information

Tumor necrosis factor receptor (TNFR) superfamily members transmit signals regulating proliferation, differentiation and apoptosis in various types of cells. TNFR-associated factors (TRAFs) are a family of proteins that were initially discovered as downstream signal transducers of the TNFR superfamily. TRAF3 contains an N-terminal ring finger/zinc finger region that is thought to be essential for downstream signaling. MIP-T3 is associated with TRAF3. MIP-T3 binds to taxol-stabilized microtubules and to tubulin in vitro, and MIP-T3 recruits TRAF3 to microtubules when both proteins are overexpressed. The MIP-T3/TRAF3 interaction requires the coiled-coil TRAF-N domain of TRAF3. This interaction may provide a novel mechanism in sequestering TRAF3 to the cytoskeletal network.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.