Thermo Fisher Scientific VAMP2 Monoclonal Antibody (GT6311)
VAMP2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC/IF에 적합. Human, Mouse, Rat 반응성. Protein G 정제, preservative-free PBS 용액 형태. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT6311 |
| Immunogen | Full length human VAMP2 recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.74 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866546 |
Target Information
The vesicle-associated membrane proteins (VAMPs), also known as synaptobrevins, are calcium-binding proteins specific to eukaryotic cells. VAMPs, together with SNAP-25 and syntaxin, form the core SNARE complex that interacts with NSF and alpha-SNAP to regulate vesicle fusion with the plasma membrane.
Clostridium tetani neurotoxin specifically cleaves VAMP. In Alzheimer’s disease, VAMP levels are significantly reduced. VAMP2 is also known as a resident protein of the insulin-sensitive GLUT4 compartment and is required for GLUT4 vesicle incorporation into the cell surface in response to insulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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