Thermo Fisher Scientific CD97 Recombinant Rabbit Monoclonal Antibody (3E5L8)
CD97 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, Western blot과 ELISA에 최적화되어 있습니다. 인간 시료에 반응하며 HEK293 세포에서 발현되었습니다. 고순도 친화 크로마토그래피 정제 제품으로 안정적인 액상 형태로 제공됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3E5L8 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 21–398 of human CD97 (NP_510966.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.072 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3093081 |
Product Specific Information
Immunogen sequence:
QDSRGCARWC PQNSSCVNAT ACRCNPGFSS FSEIITTPTE TCDDINECAT PSKVSCGKFS DCWNTEGSYD CVCSPGYEPV SGAKTFKNES ENTCQDVDEC QQNPRLCKSY GTCVNTLGSY TCQCLPGFKF IPEDPKVCTD VNECTSGQNP CHSSTHCLNN VGSYQCRCRP GWQPIPGSPN GPNNTVCEDV DECSSGQHQC DSSTVCFNTV GSYSCRCRPG WKPRHGIPNN QKDTVCEDMT FSTWTPPPGV HSQTLSRFFD KVQDLGRDSK TSSAEVTIQN VIKLVDELME APGDVEALAP PVRHLIATQL LSNLEDIMRI LAKSLPKGPF TYISPSNTEL TLMIQERGDK NVTMGQSSAR MKLNWAVAAG AEDPGPAV
Target Information
CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor constitutively expressed on granulocytes and monocytes, and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms, and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage.
Interaction of CD97 on leukocytes and CD55 on vessel cells facilitates leukocyte activation and migration into tissues. CD97 also plays a role in tumor migration and invasiveness, and is involved in T cell regulation and peripheral granulocyte homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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