Thermo Fisher Scientific GTF2E1 Recombinant Rabbit Monoclonal Antibody (23GB6310)
Western blot과 유세포분석에 적합한 재조합 토끼 단클론 항체. Human, Mouse, Rat 반응성. HEK293F 발현 시스템에서 생산. 고순도 친화 크로마토그래피 정제. -20°C 보관, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB6310 |
| Immunogen | A synthesized peptide derived from human TFIIE alpha (400–439AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The general transcription factor TFIIE plays an essential role in eukaryotic transcription initiation with RNA polymerase II and other general factors.
Human TFIIE consists of two subunits, TFIIE-alpha (57 kDa) and TFIIE-beta (34 kDa), joining the preinitiation complex after RNA polymerase II and TFIIF.
TFIIE-alpha is required for transcription initiation together with TFIIE-beta and can fully replace the natural subunit in vitro.
Its sequence includes structural motifs such as a leucine repeat, zinc finger, and helix-turn-helix, showing similarity to bacterial sigma factors, suggesting a role in transcription regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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