Thermo Fisher Scientific beta Amyloid Polyclonal Antibody
Human 및 Mouse에서 beta Amyloid 검출용 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Affinity purification으로 높은 특이성과 재현성 확보. 알츠하이머 연구 등 신경퇴행 질환 연구에 활용 가능.
- 카탈로그번호
- 600-401-253x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific beta Amyloid Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:10,000–1:30,000 |
| Immunoprecipitation (IP) | 1:1,000–1:5,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the amino terminus (aa 1–14) of human beta amyloid conjugated to KLH using maleimide. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02 M potassium phosphate, pH 7.2, with 0.15 M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at –20°C prior to opening. Aliquot contents and refreeze at –20°C or below for long-term storage. Avoid repeated freeze/thaw cycles. Centrifuge if not clear after standing at room temperature. Stable for several weeks at 4°C as an undiluted liquid. Dilute only before immediate use.
This affinity-purified antibody targets the amino-terminal end of beta amyloid and is effective for detecting human and mouse beta amyloid. Cross-reactivity with other species is possible but not determined.
Target Information
Amyloid beta peptide (Abeta/Beta-amyloid) is the major component of amyloid plaques in Alzheimer’s disease. The peptide (40–43 amino acids) is derived from the beta-amyloid precursor protein (beta APP) through sequential cleavage by beta-secretase (BACE) and gamma-secretase. Gamma-secretase, a multi-subunit complex including presenilin-1/2 and nicastrin, mediates intramembrane cleavage to release Abeta.
Abeta forms extracellular filamentous deposits found in amyloid cores, neuritic plaques, and neurofibrillary tangles. Beta amyloid accumulation is associated with Alzheimer’s disease, Lewy body dementia, Down’s syndrome, cerebral amyloid angiopathy, and other amyloidoses.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.