Thermo Fisher Scientific LZTR2 Polyclonal Antibody
LZTR2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 적합합니다. Human, Mouse, Rat 시료에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 냉장 보관(2–8°C) 권장, 장기 보관 시 -20°C. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid peptide near the carboxy terminus of human LZTR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153334 |
Product Specific Information
- A suggested positive control is mouse kidney tissue lysate.
- PA5-20903 can be used with blocking peptide PEP-1017.
Target Information
LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene.
LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation.
Recent evidence suggests a strong correlation between single nucleotide polymorphisms of LZTR2 and obesity in the Japanese population, similar to associations seen with TMEM18, GNPDA2, BDNF, FAIM2, and MC4R genes in Caucasian populations, indicating LZTR2 may play a role in metabolism and obesity risk.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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