Thermo Fisher Scientific ZSCAN4 Polyclonal Antibody
ZSCAN4 단백질을 표적하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 IHC에 적합하며 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태, 4°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid peptide near the carboxy terminus of human ZSCAN4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152831 |
Product Specific Information
- Suggested positive control: Mouse lung tissue lysate
- PA5-20901 can be used with blocking peptide PEP-1015
Target Information
Zygotic genome activation (ZGA) is the first and most critical transition event from the maternal to the embryonic genetic program, occurring mainly in the late 2-cell stage.
ZSCAN4 encodes a SCAN domain and four zinc finger domains, expressed in late 2-cell embryos and embryonic stem cells.
Loss-of-function studies using siRNA show delays in embryo development from the 2-cell to 4-cell stage.
ZSCAN4 is important for preimplantation development, telomere maintenance, and genomic stability in ES cells, suggesting its role in maintaining pluripotency in replicating stem cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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