Thermo Fisher Scientific Cytokeratin 4 (KRT4) Monoclonal Antibody (KRT4/2804)
사이토케라틴 4(KRT4)를 인식하는 마우스 단클론 항체로, IHC, ICC, Flow Cytometry 등에 사용 가능. 인간 시료 반응성. 단백질 A/G 정제, PBS 버퍼에 보존. 연구용으로만 사용.
- 카탈로그번호
- 3851-MSM4-P1ABX
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT4/2804 |
| Immunogen | Recombinant fragment (around aa 181–292) of human KRT4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratins are a subfamily of intermediate filament proteins characterized by biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight from approximately 40 kDa to 68 kDa and have isoelectric points between 4.9 and 7.8.
Individual human cytokeratins are numbered 1 to 20. Expression patterns vary by epithelial type and differentiation stage, making them useful markers in distinguishing epithelial malignancies.
Cytokeratin antibodies assist in differential tumor diagnosis using immunohistochemistry and are also valuable in cytopathology and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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