Thermo Fisher Scientific HDAC3 Monoclonal Antibody
HDAC3 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체. 인간 HDAC3 C-말단 서열을 이용한 합성 펩타이드로 면역화. ChIP assay 등 연구용에 적합. 액상 형태로 제공되며 -20°C 보관, 동결/해동 반복은 피해야 함.
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Applications
- ChIP assay (ChIP)
Tested Dilution: 5 µL / 1×10⁴ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | Raised in mouse using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal region of human HDAC3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping conditions | Dry ice |
| RRID | AB_2533891 |
Target Information
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1.
This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis.
This gene is regarded as a potential tumor suppressor gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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