Thermo Fisher Scientific SUMO-2/3 Monoclonal Antibody (SM23/496)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL

-

Immunocytochemistry (ICC/IF)

1-2 µg/mL

-

Flow Cytometry (Flow)

1-2 µg/10^6 cells

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

SM23/496

Immunogen

Recombinant human SUMO2 protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SUMO2/SUMO3,uniProtId:P61956-1,ncbiNodeId:9606,antigenRange:1-95,antigenLength:95,antigenImageFileName:6613-MSM1-P1ABX_SUMO2SUMO3_P61956-1_House_mouse.svg,antigenImageFileNamePDP:6613-MSM1-P1ABX_SUMO2SUMO3_P61956-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:SUMO2/SUMO3,uniProtId:P55854-1,ncbiNodeId:9606,antigenRange:1-103,antigenLength:103,antigenImageFileName:6613-MSM1-P1ABX_SUMO2SUMO3_P55854-1_House_mouse.svg,antigenImageFileNamePDP:6613-MSM1-P1ABX_SUMO2SUMO3_P55854-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Predicted to show a broad species reactivity

Target Information

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.