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Thermo Fisher Scientific p19ARF Polyclonal Antibody
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Thermo Fisher Scientific p19ARF Polyclonal Antibody

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Thermo Fisher Scientific p19ARF Polyclonal Antibody는 마우스 및 랫트 반응성을 가진 Rabbit IgG 항체로, Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, p19ARF 종양 억제 단백질 연구에 활용됩니다.

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마지막 업데이트 2025. 08. 02. 오전 06:36
Thermo Fisher Scientific PA130670 p19ARF Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
824,100원VAT 포함 906,510원

Thermo Fisher Scientific · Thermo Fisher Scientific p19ARF Polyclonal Antibody

Thermo Fisher Scientific p19ARF Polyclonal Antibody

Applications and Tested Dilutions

Application Tested Dilution Publications
Western Blot (WB) 2 µg/mL View 3 publications
Immunohistochemistry (IHC) - View 1 publication
Immunohistochemistry (Paraffin) (IHC (P)) 10 µg/mL View 2 publications
Immunohistochemistry (Frozen) (IHC (F)) 1 µg/mL -
Immunocytochemistry (ICC/IF) 1:50–1:100 View 1 publication
ELISA 1:100–1:2,000 -
Immunoprecipitation (IP) - View 1 publication
ChIP assay (ChIP) - View 1 publication

Product Specifications

Specification Description
Species Reactivity Mouse, Rat
Published Species Human, Mouse, Rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide conjugated to KLH, derived from a sequence within residues 50–150 of mouse p19ARF
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Antigen affinity chromatography
Storage Buffer Tris citrate/tris phosphate, pH 7.0–8.0
Contains 0.1% sodium azide
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Conditions Wet ice
RRID AB_1956784

Product Specific Information

PA1-30670 recognizes p19ARF (Uniprot ID Q64364).
Store product as a concentrated solution and centrifuge briefly prior to opening the vial.


Target Information

In humans, the multiple tumor suppressor 1 locus (MTS1) encodes two unrelated genes, p16INK4a and p19ARF.
Although both act as cell proliferation inhibitors, their mechanisms differ:

  • p19ARF functions in a p53-dependent pathway to counteract uncontrolled proliferation and oncogenic signals.
  • Mice lacking the p19ARF gene rapidly develop a broad spectrum of tumors, highlighting its importance as a tumor suppressor.
  • p19ARF also helps prevent transforming signals from various oncoproteins via the p53 regulatory loop.

These findings emphasize the crucial role of p19ARF in cell cycle control and tumor suppression.


For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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