Thermo Fisher Scientific TIA-1 Polyclonal Antibody
TIA-1 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인간 및 생쥐 반응성 확인. 고순도 정제 및 안정적인 액상 형태로 제공.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (PKSTYESNTKQ) corresponding to the internal amino acids of TIA1 (aa 189–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10986154 |
Product Specific Information
This antibody is predicted to react with canine, mouse, and rat based on sequence homology.
Tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from:
- WNT protein (WNT3A) to stabilize beta-catenin
- Noggin, a bone morphogenetic protein inhibitor
Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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