Thermo Fisher Scientific LAMTOR2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LAMTOR2. Recombinant protein control fragment (Product #RP-102170). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LAMTOR2,uniProtId:Q9Y2Q5-1,ncbiNodeId:9606,antigenRange:3-118,antigenLength:125,antigenImageFileName:PA5-52056_LAMTOR2_Q9Y2Q5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52056_LAMTOR2_Q9Y2Q5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643266

Product Specific Information

Immunogen sequence: RPKALTQVLS QANTGGVQST LLLNNEGSLL AYSGYGDTDA RVTAAIASNI WAAYDRNGNQ AFNEDNLKFI LMDCMEGRVA ITRVANLLLC MYAKETVGFG MLKAKAQALV QYLEEP

Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

Target Information

The late endosomal/lysosomal adaptor MAPK and MTOR activator 2 (LAMTOR2) protein belongs to the LAMTOR family of proteins, and together with LAMTOR3 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling. This complex is involved in the regulation of late endosomal traffic and cellular proliferation and plays a role in cellular host defense against Salmonella infection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.