Thermo Fisher Scientific AGTR2 Recombinant Rabbit Monoclonal Antibody (SN71-03)
AGTR2 단백질을 인식하는 Recombinant Rabbit Monoclonal Antibody로 높은 특이성과 민감도를 제공합니다. Western Blot에 적합하며, 인체·마우스·랫트 반응성을 보입니다. 단백질 A로 정제된 액상형 항체로 안정적인 장기 보관이 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SN71-03 |
| Immunogen | Synthetic peptide within Human Angiotensin II Type 2 Receptor (aa 311–363) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809578 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select the best candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Angiotensin II is a potent vasopressor hormone and a key regulator of aldosterone secretion, acting through AGTR1 and AGTR2 receptors. It controls blood pressure and volume in the cardiovascular system and plays a major role in kidney and urinary tract development.
AGTR2, a seven-transmembrane G protein-coupled receptor, differs from AGTR1 by lacking most classic GPCR signaling features. It is involved in neurite outgrowth induction, inhibition of cellular proliferation, and mediation of vasoconstriction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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