Thermo Fisher Scientific GluR2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human GluR2 (GRIA2). Validated for WB and IP applications. Preservative-free formulation with high purity via Protein A and antigen affinity chromatography. Suitable for neuroscience and synaptic plasticity research.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 0.5–2 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the center region of the Human GRIA2/GLUR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788713 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human GluR2.
Target Information
The ion channels activated by glutamate are typically divided into two classes:
- Those sensitive to N-methyl-D-aspartate (NMDA), designated NMDA receptors (NMDAR)
- Those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA), known as AMPA receptors (AMPAR)
AMPARs are composed of four distinct glutamate receptor subunits (GluR1–4) and play key roles in excitatory neurotransmission in the brain.
The GluR2 subunit is thought to play a central role in synaptic plasticity, such as long-term depression (LTD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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