Thermo Fisher Scientific TNFSF15 Monoclonal Antibody (1A4)
TNFSF15 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료에 반응하며 비결합(Unconjugated) 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, PBS 완충액에 보존되어 있습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A4 |
| Immunogen | TNFSF15 (AAH74941.1, 72 a.a. approximately 251 a.a) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
LKGQEFAPSH QQVYAPLRAD GDKPRAHLTV VRQTPTQHFK NQFPALHWEH ELGLAFTKNR
MNYTNKFLLI PESGDYFIYS QVTFRGMTSE CSEIRQAGRP NKPDSITVVI TKVTDSYPEP
TQLLMGTKSV CEVGSNWFQP IYLGAMFSLQ EGDKLMVNVS DISLVDYTKE DKTFFGAFLLTarget Information
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is abundantly expressed in endothelial cells but not in B or T cells. Expression is inducible by TNF and IL-1 alpha. This cytokine acts as a ligand for receptors TNFRSF25 and TNFRSF21/DR6, can activate NF-kappaB and MAP kinases, and functions as an autocrine factor inducing apoptosis in endothelial cells. It also inhibits endothelial cell proliferation, functioning as an angiogenesis inhibitor. An additional isoform from an alternatively spliced transcript variant has been reported, though its sequence has not been determined.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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