Thermo Fisher Scientific TNFSF15 Monoclonal Antibody (4F1)
TNFSF15 단백질을 인식하는 Mouse IgG1 단클론 항체로 인간 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 친화 크로마토그래피로 정제된 액상 형태입니다. TNFSF15 관련 세포 신호 및 염증 연구에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F1 |
| Immunogen | TNFSF15 (AAH74941.1, 72–251 a.a) partial recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LKGQEFAPSH QQVYAPLRAD GDKPRAHLTV VRQTPTQHFK NQFPALHWEH ELGLAFTKNR MNYTNKFLLI PESGDYFIYS QVTFRGMTSE CSEIRQAGRP NKPDSITVVI TKVTDSYPEP TQLLMGTKSV CEVGSNWFQP IYLGAMFSLQ EGDKLMVNVS DISLVDYTKE DKTFFGAFLL
Target Information
The protein encoded by this gene is a cytokine belonging to the tumor necrosis factor (TNF) ligand family. It is abundantly expressed in endothelial cells but not in B or T cells. Expression is inducible by TNF and IL-1α. This cytokine binds to receptors TNFRSF25 and TNFRSF21/DR6, activates NF-kappaB and MAP kinases, and induces apoptosis in endothelial cells. It also inhibits endothelial cell proliferation, functioning as an angiogenesis inhibitor. An additional isoform from an alternatively spliced transcript variant has been reported but not fully characterized.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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