Thermo Fisher Scientific MCM7 Monoclonal Antibody (47DC141 (DCS-141))
MCM7 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, WB, IHC, ICC/IF, IP 등 다양한 응용에 적합합니다. 인간, 마우스, 개 등 여러 종에서 반응하며, 액상 형태로 4°C 보관이 필요합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 4 publications |
| Immunohistochemistry (IHC) | – | View 9 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1.0 µg/mL | – |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | – |
| Immunoprecipitation (IP) | 2 µg/mg protein lysate | – |
Product Specifications
| Specification | Detail |
|---|---|
| Published Species | Dog, Human, Mouse, Rabbit |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 47DC141 (DCS-141) |
| Immunogen | Recombinant hCDC47 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11009501 |
Product Specific Information
MA5-14291 targets CDC47 in IF, IHC (P), IP, and WB applications and shows reactivity with Canine, Human, Mouse, Rat, and Xenopus laevis samples.
The MA5-14291 immunogen is recombinant hCDC47 protein.
Target Information
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) essential for the initiation of eukaryotic genome replication.
The hexameric complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC), involved in replication fork formation and recruitment of DNA replication-related proteins.
The MCM complex consisting of MCM2, 4, 6, and 7 exhibits DNA helicase activity and may act as a DNA unwinding enzyme.
Cyclin D1-dependent kinase CDK4 associates with this protein and may regulate its binding with tumor suppressor RB1/RB.
Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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