Thermo Fisher Scientific Cdc6 Monoclonal Antibody (DCS-180)
CDC6 단백질을 인식하는 Mouse monoclonal antibody (Clone DCS-180). Western blot 및 Immunoprecipitation에 사용 가능. Human, Mouse, Rat 시료에 반응. Recombinant human CDC6 protein으로 면역화. 단백질 복제 개시 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 5 publications |
| Immunoprecipitation (IP) | 2 µg/mL | View publications |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | DCS-180 |
| Immunogen | Recombinant human CDC6 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10980382 |
Product Specific Information
MA5-14314 targets CDC6 in IP and WB applications and shows reactivity with Human samples.
The MA5-14314 immunogen is recombinant human CDC6 protein.
Target Information
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication.
This protein functions as a regulator at the early steps of DNA replication.
It localizes in the cell nucleus during the G1 phase of the cell cycle, but translocates to the cytoplasm at the start of the S phase.
The subcellular translocation of this protein is regulated through phosphorylation by Cdks.
Transcription of this protein is regulated in response to mitogenic signals via transcriptional control mechanisms involving E2F proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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