Thermo Fisher Scientific HSD3B2 Polyclonal Antibody
HSD3B2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Human과 Mouse 시료에 반응합니다. Western blot과 ELISA에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HSD3B2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human HSD3B1 + HSD3B2 (amino acids 101–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720396 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. Purity is greater than 95% as determined by SDS-PAGE.
Target Information
3 beta-hydroxysteroid dehydrogenase (3β-HSD), also known as HSD3B1 or HSD3B2, is a bifunctional enzyme essential for the synthesis of all classes of hormonal steroids. Two human 3β-HSD proteins, type I (HSD3B1) and type II (HSD3B2), are encoded by different genes and function in distinct tissues. The type I enzyme is localized to the endoplasmic reticulum membrane and expressed in skin and placenta. It catalyzes the oxidative conversion of Δ5-ene-3β-hydroxy steroids and various ketosteroids. Defects in the gene encoding 3β-HSD are associated with conditions such as classic salt wasting, genital ambiguity, hypogonadism, insulin-resistant polycystic ovary syndrome (PCOS), and increased susceptibility to prostate cancer. Congenital deficiency of 3β-HSD activity can cause severe steroid depletion, which may be lethal in young children.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.