Thermo Fisher Scientific BAG5 Monoclonal Antibody (OTI5F1), TrueMAB
Human BAG5 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Western blot에 최적화되어 있음. 고순도 친화 크로마토그래피 정제 제품이며, PBS/BSA/glycerol buffer에 보존됨. 인간 신경 세포 사멸 연구 및 BAG 단백질 상호작용 분석에 유용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 290–440 of human BAG5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
It has been hypothesized that the BAG-5 protein induces the death of nigral neurons through its predicted interaction with hsp70, causing increased protein aggregation and cell death by disinhibition of hsp70’s anti-apoptotic function. BAG-5 is believed to play an important role in neuronal death mechanisms and may act as a modulator of the hsp70/hsp40 chaperone axis. It may also coordinate localization or modulation of other BAG-containing proteins via BAG–BAG heterodimerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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