Thermo Fisher Scientific IL34 Monoclonal Antibody (OTI4F2), TrueMAB
인간 IL-34 단백질(aa 77-242)에 특이적인 Mouse monoclonal antibody. Western blot에서 1:2,000 희석으로 검증됨. 비표지(Unconjugated) 액상 형태로 제공되며, PBS/BSA/glycerol 완충액에 보관. -20°C에서 보관하며 동결/해동 반복은 피해야 함.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 77–242 of human IL34 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor (CSF-1R/CD115), which is shared with M-CSF. Although IL-34 has no amino acid sequence homology to M-CSF, they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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