Thermo Fisher Scientific BAG5 Monoclonal Antibody (OTI4E5), TrueMAB
인간 BAG5 단백질(aa 290-440)을 인식하는 mouse IgG1 단클론 항체. Western blot에 1:2,000 희석으로 사용 가능. 액상 형태로 1 mg/mL 농도, PBS/BSA/glycerol 버퍼에 보관. 신경세포 사멸 관련 BAG5 연구용에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 290–440 of human BAG5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
It has been hypothesized that the BAG-5 protein induces the death of nigral neurons through its predicted interaction with hsp70, leading to increased protein aggregation and cell death by disinhibition of hsp70’s anti-apoptotic function. BAG-5 is believed to play an important role in neuronal death mechanisms. It may also modulate the hsp70/hsp40 chaperone axis or interact with other BAG-containing proteins via BAG-BAG heterodimerization.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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