Thermo Fisher Scientific FPR1 (extracellular) Polyclonal Antibody
FPR1 단백질의 세포외 영역을 인식하는 Rabbit Polyclonal 항체. Western blot 및 유세포분석(Flow Cytometry)에 적합. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 상태로 제공. 염증 관련 연구 및 GPCR 신호전달 연구에 활용 가능.
- 카탈로그번호
- AFR-001-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific FPR1 (extracellular) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Flow Cytometry (Flow) | 2.5 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)NFSPWTNDPKERIN, corresponding to amino acid residues 179–192 of human FPR1 (2nd extracellular loop) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution:
25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on the sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
Reconstituted solution can be stored at 4°C for up to 1 week. For longer storage, prepare small aliquots and store at -20°C.
Avoid multiple freeze/thaw cycles.
Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
FPR1 (Formyl Peptide Receptor 1) is a member of chemoattractant/chemokine GPCRs expressed mainly on leukocytes, neutrophils, and monocytes.
It is a seven-transmembrane, pertussis toxin-sensitive GPCR that binds formylated peptides generated by bacteria, leading to leukocyte trafficking to sites of inflammation.
Ligand binding activates multiple effectors, including phospholipase C, resulting in calcium mobilization and PKC activation.
FPR signaling influences actin cytoskeleton polarization, integrin activation, cell migration, phagocytosis, degranulation, and reactive oxygen intermediate release.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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