Thermo Fisher Scientific GM-CSF Polyclonal Antibody
Thermo Fisher Scientific의 GM-CSF Polyclonal Antibody는 인간 GM-CSF를 인식하는 sheep 유래 IgG 항체로 ELISA에 적합합니다. 액상 형태로 제공되며, PBS 버퍼와 sodium azide를 포함합니다. -20°C에서 보관하며 반복 동결/해동을 피해야 합니다.
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Applications
ELISA (ELISA)
- Tested Dilution: 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant human GM-CSF (aa 18–144) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1090209 |
Target Information
The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space.
This gene is located in a cluster of related genes at chromosome region 5q31, which has been associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13.
The gene is involved in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome.
Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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