Thermo Fisher Scientific RAMP2 Polyclonal Antibody
RAMP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로, 0.1 mg/mL 농도. 연구용으로만 사용.
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Thermo Fisher Scientific RAMP2 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF): Tested dilution 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human RAMP2. Recombinant protein control fragment (Product #RP-106369) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662186 |
Product Specific Information
Immunogen sequence:
PLPTTGTPGSE GGTVKNYETA VQFCWNHYKD QMDPIEKDWC DWAMISRPYS TLRDCLEHFA ELFDLGFPNP LAERIIFETH QIHFANCSLV QP
Highest antigen sequence identity to the following orthologs:
- Mouse: 55%
- Rat: 56%
Target Information
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus.
RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor depending on the RAMP expressed.
In the presence of RAMP2, CRLR functions as an adrenomedullin receptor. RAMP2 is involved in core glycosylation and transportation of the adrenomedullin receptor to the cell surface.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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