Thermo Fisher Scientific L-Plastin Polyclonal Antibody
L-Plastin 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 적용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C-terminus of human L-plastin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: HL60 cells
- Cellular location: Cytoplasmic
Target Information
L-plastin is a leukocyte-specific actin bundling protein from the fimbrin family. It has two actin-binding domains and two EF-hand type calcium-binding domains. It is phosphorylated on a serine residue in its headpiece region in response to inflammatory stimuli.
It may regulate integrin-mediated adhesion in leukocytes and is expressed in most human cancer cell lines derived from solid tumors. Expression is upregulated by testosterone in androgen receptor-positive prostate and breast cancer cells via androgen receptor binding elements upstream of the gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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