Thermo Fisher Scientific Nonstructural protein 2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300-1:2,000

-

Immunohistochemistry (IHC)

1:300-1:2,000

-

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Virus

Published species

Not Applicable

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from aa region 50-80 of Influenza A virus Nonstructural protein 2 conjugated to an immunogenic carrier protein was used as the antigen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: Nonstructural protein 2.

Target Information

Influenza viruses consists of three types (Influenza A, B, and C), which make up three of the five genera in the Orthomyxoviridae family. Commonly know as the flu, influenza strains can affect both birds and mammals. Influenza strains form roughly spherical particles and are similar in composition with viral envelope containing two main types of glycoproteins (hemagglutinin and neuraminidase), wrapped around the central core of the viral RNA genome and other viral proteins that package and protect the RNA. Unusually for a virus, the influenzavirus genome is not a single piece of nucleic acid; rather a seven to eight segmented fragments of negative-sense RNA with each fragment expressing different viral proteins. Influenza spreads seasonally, resulting in about three to five million yearly cases of severe illness and about 250,000 to 500,000 deaths annually or into the millions in pandemic years. Two distinct non-structural proteins NS1 and NS2 are translated from one of the eight RNA segments by using different reading frames.The influenza A virus NS2 is located in the nucleus and the cytoplasm. NS2 is essential for nuclear export of influenza virus ribonucleoprotein (RNP) complexes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.