
Thermo Fisher Scientific ATR Polyclonal Antibody
Thermo Fisher Scientific의 ATR Polyclonal Antibody는 인간 ATR 단백질의 중심 잔기 서열에 대응하는 합성 펩타이드로부터 제작된 rabbit IgG 항체입니다. Western blot에 적합하며, DNA 손상 반응 및 세포 주기 조절 연구에 활용됩니다. 액상 형태로 -20°C 보관합니다.
- 카탈로그번호
- PA517265
- 판매단위
- pk
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Thermo Fisher Scientific ATR Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution
- 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to central residues of human ATR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 14 µg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10975231 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. It can phosphorylate and activate several proteins involved in inhibition of DNA replication and mitosis, and promotes DNA repair, recombination, and apoptosis. This protein is also essential for fragile site stability and centrosome duplication. Defects in this gene cause Seckel syndrome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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