Thermo Fisher Scientific alpha-Tubulin Polyclonal Antibody
Rabbit polyclonal antibody recognizing alpha-Tubulin, validated for WB and IP. Targets residues 175–225 of human tubulin alpha 1a. Supplied as a liquid, 1 mg/mL, stored at 4°C. Predicted cross-reactivity with multiple species. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µL/mg of lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 175 and 225 of human tubulin alpha 1a |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
Predicted reactivity by homology: Drosophila, Porcine, Xenopus laevis, Xenopus tropicalis, Rat, Chimpanzee, Chicken, Bovine.
Target Information
Alpha Tubulin is part of a heterodimer consisting of alpha and beta tubulin subunits, each approximately 55 kDa. These heterodimers form microtubules—cylindrical filamentous structures present in almost all eukaryotic cells. Microtubules provide structural support, facilitate intracellular transport, and play a key role in mitosis.
Gamma tubulin is critical for microtubule nucleation. Alpha and beta tubulin genes are highly conserved among species, with alpha tubulin showing strong similarity to mouse and rat Tuba1 genes. Expression is predominantly found in morphologically differentiated neurologic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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