Thermo Fisher Scientific SOX10 Polyclonal Antibody
SOX10 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF, IP 등에 사용 가능. 다양한 종에서 예측 반응성을 보이며, 신경능선 및 말초신경계 연구에 적합. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:10,000–1:25,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Immunoprecipitation (IP) | 50–100 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 416 and 466 of human DOM; WS4; PCWH; WS2E; WS4C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Predicted reactivity by homology: Porcine, Xenopus laevis, Xenopus tropicalis, Rat, Chicken
- Immunocytochemistry: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
Target Information
SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in embryonic development and cell fate determination.
It may act as a transcriptional activator after forming a complex with other proteins and functions as a nucleocytoplasmic shuttle protein.
SOX10 is essential for neural crest and peripheral nervous system development.
Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung diseases.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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