Thermo Fisher Scientific Il-2 Monoclonal Antibody (A150D8H10), Biotin
Thermo Fisher Scientific의 IL-2 단클론 항체(A150D8H10), Biotin은 돼지 IL-2를 인식하는 Mouse IgG1 항체로, Sandwich ELISA 검출용으로 최적화됨. Biotin 결합형으로 높은 특이성과 안정성을 제공하며, 4°C에서 보관 가능.
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Applications
ELISA (ELISA): Assay-dependent
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Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Pig |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A150D8H10 |
| Immunogen | Recombinant swine IL-2 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536420 |
Product Specific Information
This product is recommended as a detection antibody in Sandwich ELISA applications.
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine that plays a crucial role in:
- Proliferation of activated T cells
- Differentiation of B cells, natural killer cells, monocytes, and macrophages
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is shared by IL-4 and IL-7.
Expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mechanism for precise gene expression.
Disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease, underscoring its essential role in immune response to antigenic stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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