Thermo Fisher Scientific EpCAM Monoclonal Antibody (VU-1D9), FITC
EpCAM 단백질을 인식하는 VU-1D9 클론의 FITC 결합 마우스 단일클론 항체. Flow Cytometry 및 Immunocytochemistry에 적합. 인간 시료에서 검증됨. 4°C 암소 보관, 연구용으로만 사용.
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Thermo Fisher Scientific EpCAM Monoclonal Antibody (VU-1D9), FITC
Applications
Immunocytochemistry (ICC/IF)
Tested dilution: Not specified
View 1 publicationFlow Cytometry (Flow)
Tested dilution: 20 µL/1x10^6 cells
View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VU-1D9 |
| Immunogen | Small cell lung carcinoma cell line H69 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Storage conditions | 4°C, store in dark |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2534535 |
Additional Formats
Target Information
Ep-CAM (epithelial adhesion molecule, ESA) is a transmembrane glycoprotein expressed in epithelial cells, with a molecular weight of approximately 40 kDa. It functions as a Ca²⁺-independent homotypic adhesion molecule and influences cell cycle, proliferation, and metabolism by inducing proto-oncogene c-myc and cyclins A and E.
Ep-CAM-mediated adhesions negatively regulate cadherin-mediated adhesions, affecting epithelial differentiation and growth. Overexpression is associated with enhanced epithelial proliferation and is a marker for tumors of epithelial lineage.
Ep-CAM is expressed on the baso-lateral surface of most simple epithelia and many carcinoma types, distinguishing adenocarcinomas from pleural mesotheliomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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