Thermo Fisher Scientific CD81 Monoclonal Antibody (M38), FITC

Applications

Immunocytochemistry (ICC/IF)

• Tested dilution: 정보 없음
• 참고 문헌: 1건

Flow Cytometry (Flow)

• Tested dilution: 20 µL / 1×10⁶ cells
• 참고 문헌: 5건

Product Specifications

Additional Formats

• Unconjugated (MA1-10290)
• Alexa Fluor 488 (MA5-44132)
• PE (MA1-10292)
• Custom conjugation available upon request

Product Specific Information

This antibody reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on the majority of cells.

Target Information

CD81 (TAPA-1) is a tetraspanin family protein expressed on most nucleated cells, particularly germinal center B cells. It forms complexes with other tetraspanins, integrins, coreceptors, and MHC molecules, influencing cell adhesion, morphology, activation, proliferation, and differentiation of B and T cells.
In muscle cells, CD81 promotes fusion and supports myotube maintenance. It also serves as a receptor for hepatitis C virus.
CD81 is implicated in various cellular processes and may play a role in tumor suppression. Antibodies against CD81 exhibit anti-proliferative effects on lymphoid cell lines.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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