Thermo Fisher Scientific HAX1b Polyclonal Antibody
HAX1b 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 Human, Mouse, Rat에서 반응. 항원 친화 크로마토그래피로 정제, 액상 형태로 1 mg/mL 농도. 연구용으로만 사용.
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Thermo Fisher Scientific HAX1b Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1–2 µg/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 10 amino acid peptide near the amino terminus of human Hax1b |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage store at −20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157683 |
Product Specific Information
- A suggested positive control is mouse brain tissue lysate.
- PA5-20650 can be used with blocking peptide PEP-0770.
Target Information
The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay based on its ability to bind to the hematopoietic cell-specific protein 1 (HS-1).
Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including BH1- and BH2-like domains.
It interacts with HIV viral protein R (Vpr), linked to T-cell apoptosis via activation of caspases 3 and 9.
Hax1-mediated processing of HtrA2 (Omi) by mitochondrial protease PARL supports lymphocyte and neuron survival under cytokine-limiting conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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