Thermo Fisher Scientific Synaptophysin Recombinant Mouse Monoclonal Antibody (rSYP, 6856)
Synaptophysin 단백질을 인식하는 마우스 유래 재조합 단클론 항체로, IHC(P) 검증 완료. 신경 말단 및 신경내분비 종양 마커 연구에 적합. Protein A/G 정제, PBS 완충액에 보존, 방부제 무첨가. 연구용으로만 사용 가능.
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- 6855-MSM6-P1ABX
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rSYP, 6856 |
| Immunogen | Recombinant fragment (around aa 224–313) of human Synaptophysin (SYP) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C or −80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles of nearly all neurons. It possesses four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting a role in synaptic vesicle endocytosis. Synaptophysin is involved in the regulation of short-term and long-term synaptic plasticity and is widely used as a marker for nerve terminals and in differentiating neuroendocrine tumors. Mutations in the gene are associated with X-linked mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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