Thermo Fisher Scientific NEFL Polyclonal Antibody, MaxPab
NEFL 단백질을 표적하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 in situ PLA에 최적화되어 있으며, 인간 시료에 반응. PBS(pH 7.4) 용액 내 액상 형태로 제공되며, 친화 크로마토그래피로 정제됨.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| in situ PLA (PLA) | 1:1200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | NEFL (NP_006149.2, 1 a.a. ~ 543 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence (NEFL):
MSSFSYEPYY STSYKRRYVE TPRVHISSVR SGYSTARSAY SSYSAPVSSS LSVRRSYSSS SGSLMPSLEN LDLSQVAAIS NDLKSIRTQE KAQLQDLNDR FASFIERVHE LEQQNKVLEA ELLVLRQKHS EPSRFRALYE QEIRDLRLAA EDATNEKQAL QGEREGLEET LRNLQARYEE EVLSREDAEG RLMEARKGAD EAALARAELE KRIDSLMDEI SFLKKVHEEE IAELQAQIQY AQISVEMDVT KPDLSAALKD IRAQYEKLAA KNMQNAEEWF KSRFTVLTES AAKNTDAVRA AKDEVSESRR LLKAKTLEIE ACRGMNEALE KQLQELEDKQ NADISAMQDT INKLENELRT TKSEMARYLK EYQDLLNVKM ALDIEIAAYR KLLEGEETRL SFTSVGSITS GYSQSSQVFG RSAYGGLQTS SYLMSTRSFP SYYTSHVQEE QIEVEETIEA AKAEEAKDEP PSEGEAEEEE KDKEEAEEEE AAEEEEAAKE ESEEAKEEEE GGEGEEGEET KEAEEEEKKV EGAGEEQAAK KKD
Target Information
Neurofilaments are intermediate filament proteins specifically found in neurons and are composed of three major proteins: NF-L, NF-M, and NF-H.
- NF-L (Light chain): Low molecular weight subunit (~70 kDa)
- NF-M (Medium chain) and NF-H (Heavy chain): Higher molecular weight subunits (NF-H: 180–220 kDa)
These proteins are critical for maintaining neuronal caliber and exhibit tissue-specific and developmentally regulated expression.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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