Thermo Fisher Scientific CaMKII alpha/beta/delta Polyclonal Antibody
CaMKII alpha/beta/delta 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. WB, IHC, ICC 등 다양한 응용에 적합하며 인간, 생쥐, 랫트 반응성 확인됨. 고순도 친화 크로마토그래피 정제, 액상 형태로 안정적 보관 가능.
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CAMK2A (Accession Q9UQM7), corresponding to amino acid residues S279–E329. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818491 |
Product Specific Information
Antibody detects endogenous levels of total CaMKII alpha/beta/delta.
Target Information
The Ca²⁺/calmodulin-dependent protein kinases (CaM kinases) are a subfamily of serine/threonine kinases including CaMKI, CaMKII, and CaMKIV.
CaMKII is ubiquitously expressed and activated by Ca²⁺ and calmodulin (CaM), regulating cell cycle and transcription.
Four CaMKII isozymes (alpha, beta, gamma, delta) may be co-expressed in tissues.
CaMKII alpha is autophosphorylated on Thr286 upon Ca²⁺/CaM binding, a process known as Ca²⁺/CaM trapping, related to synaptic information encoding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-99558_CaMKII_alphabetadelta_Q9UQM7-1_Rabbit.svg, PA5-99558_CaMKII_alphabetadelta_Q9UQM7-1_Rabbit_PDP.jpeg)
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