Thermo Fisher Scientific CD4 Monoclonal Antibody (UMAB64), UltraMAB
인간 CD4 단백질을 인식하는 Mouse IgG2b 단클론 항체로 다양한 면역학적 분석에 적합. WB, IHC, ICC 등에서 사용 가능. 친화 크로마토그래피로 정제된 액상 형태이며 PBS/BSA/glycerol 버퍼에 보관. 연구용 전용 제품.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| Miscellaneous PubMed (Misc) | – | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB64 |
| Immunogen | Full-length human recombinant CD4 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is mainly expressed in T helper cells but can also be found in monocytes, macrophages, and dendritic cells. Tissue-level expression includes thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut. CD4 assists in T-cell activation through interaction with the T-cell receptor complex and Lck kinase. It may also mediate neuronal damage in infectious and immune-related CNS diseases. Multiple alternatively spliced transcripts are known (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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